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By Whiting P, Rutjes AWS, Dinnes J, Reitsma JB, Bossuyt PMM, Kleijnen J

10.1126/science.1101738 32 DavidsonW

The association of Fas with these raft markers in aged RBCs suggests that lipid rafts play a crucial role in initiating and regulating the extrinsic death pathway in erythrocytes

Many diseases are associated with increased inflammation which is also a potent inducer of free radical production

In support of a possible role for nucleolin in mediating GPx-1 transcript stability, nucleolin has been reported to bind to the 3 UTR of the human GPx-1 transcript (394)
