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The transition from the presence to the absence of ABTS + can be observed by the changes in the UVVis characteristic absorption peak

The systemic bioavailability of the drug (F) can be predicted from the extent of absorption (f) and the extraction ratio (ER): A drug such as morphine is almost completely absorbed (f = 1), so that loss in the gut is negligible

In preclinical models, IPA has been shown to enhance the expression of tight junction proteins in the BBB, reduce the severity of neuroinflammation, and preserve cognitive performance after CNS injury (Deng et al., 2024)