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2018;391(Suppl 2):S5
77 , 78 , 79 , 80 The end result of these changes is the production of rigid, non-deformable erythrocytes that are susceptible to stagnation and destruction by reticuloendothelial macrophages in the spleen and liver
Azelaic acid slows down excess pigment formation by inhibiting tyrosinase (an enzyme involved in melanin production)
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Quantitatively, histamine-evoked Ca rises were increased in amplitude (%R/R 0 Fura ratio ) by ~ 70%, whereas AUC, reflecting the amount of stored Ca released via the PLC/IP pathway by the agonist, was unchanged
