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Mechanistic links between MEK1/2ERK1/2 signaling and histone acetylation have been extensively studied, particularly in the context of memory formation ( We have also previously shown that elevated ROS can activate the PI3K/AKT pathway in hPSCs (Xie et al., 2019)
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doi:10.1038/s41467-019-09192-z

After confirmation of PCOS induction, Quercetin (15 mg/kg/day) was administered via oral gavage for 30 days post-induction

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