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Acetylation of p53 activates transcription through recruitment of Coactivators/histone acetyltransferases

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d, e , Control and oncogenic RAS-induced senescent IMR90 cells with or without TXNRD1 knockdown or treatment with a pharmacological TXNRD1 inhibitor Tri-1 (5 M) were subjected to SA--gal staining or colony formation assays ( d )