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Figure 4 Inhibitory Effects on Key Enzymes in l-2HG Pathway The finding that at higher iron concentrations less glutarate and more l-2HG accumulated, while the combined concentration of glutarate plus l-2HG was highest at the lowest iron concentration indicated bottlenecks

232 Overall, this upregulation of BDNF by Wnt/-catenin signaling contributes to nerve repair during an ischemic stroke by promoting neurogenesis and neuronal survival

Johnson LK, Holven KB, Nordstrand N, Mellembakken JR, Tanbo T, Hjelmesth J

However, pantoprazole has been shown to reduce the expression of zinc transporter Zip8 and increase the expression of the transcription factor CREM

MATERIALS AND METHODS 2.1