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228 Furthermore, CD8 + T cells expressing senescence-associated molecules such as LAG-3 and PD-1-related molecules are associated with an unfavorable prognosis in CLL patients receiving CAR-T cell therapy
The extensive R-domain and NBD1 interactions increase the ATPase rate in a manner consistent with CFTR, where R-domain phosphorylation potentiates ATP binding and hydrolysis but otherwise does not induce transport activity alone 34
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