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For example, a distinct subset of astrocytes characterized by LAMP1 and TRAIL1 (LAMP1 + TRAIL + astrocytes) plays a critical role in limiting CNS inflammation in EAE mice [256]
Indeed, an element of this redundancy may stem from Retromers hub-like ability to regulate several RABs linked to endosomal cargo recycling
10.1056/NEJMra071014 20 EstevezB.DuX
Local insulin-like growth factor-II mediates prolactin-induced mammary gland development
Useful for anterior segment issues less relevant for retinal diseases
