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Quick Comparison Table: When tablets are enough: Mild or early B12 deficiency You have no absorption issues Maintenance doses after recovery When injection is better: Severe nerve damage or neuropathy Pernicious anemia (body can't absorb B12 from food) Post-surgery patients with gut issues What Research Says: A study published by the NIH (National Institutes of Health) found that intramuscular B12 injections showed significantly faster neurological recovery compared to oral supplements in patients with severe deficiency

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In one study, high homocysteine levels went from 14.7 down to 10.2 nmol/ml following methyl B12 shots