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The primary mechanism of action involves B12s essential role in several enzymatic processes crucial for health

[DOI] [PubMed] [Google Scholar] 12.Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, Pirinen E, Pulinilkunnil TC, Gong F, Wang YC, Cen Y, Sauve AA, Asara JM, Peroni OD, Monia BP, Bhanot S, Alhonen L, Puigserver P, Kahn BB

NNMT inhibition spares NAD+ and SAM (methyl donor) pools, increases adipocyte energy expenditure, and shifts metabolism toward fat oxidation

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