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It could be cancer destroying healthy cells and releasing B12 back to the blood, a bad liver that can no longer store B12, or an increased production of the transport protein haptocorrin, to which blood B12 binds

J Neurosci 28:50075017

doi: 10.1210/jc.2007-1403 195 AuriemmaRSPivonelloRPeroneYGrassoLFSFerreriLSimeoliCet al

Where as the effects may be similar, The way they influence the bodies hormonal balancing is working on quite different systems

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