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Although it is not well known whether loss of intestinal barrier per se in IBD patients is causal to bone loss in these patients (see chapter on IBD and bone for further details), our lab has shown that intestinal inflammation without weight loss in an IBD model can lead to significant bone loss suggesting a link [85]

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However, cycling prevents potential receptor desensitization, allows integration of natural healing, and reflects appropriate caution given limited long-term human data

ISBN 978-90-04-26953-8