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While we also saw induction of an ATF-4 response in cells starved of serine and glycine, we found that the dramatic drop in serine availability seen in response to both serine and glycine starvation and PHGDH inhibition in vitro led to a more profound inhibition of translation that prevented the induction of the protective ATF-4 response

10.1002/jbt.21423 J

[DOI] [PMC free article] [PubMed] [Google Scholar] 14.Passeron T, Lim HW, Goh CL, Kang HY, Ly F, Morita A, et al

The first group of pregnant rats (nine dams) received no treatment during pregnancy and delivered spontaneously

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