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The inhibition of the CySS/Glu antiporter system reduces GSH synthesis and GPX4 inactivation, leading to the accumulation of polyunsaturated fatty acids (PUFA) and ROS, and causing membrane integrity damage and ferroptosis (Friedmann Angeli and Conrad, 2018
doi: 10.2174/138920111796117300
It shows that most times, there can be a healthy difference noticeable from the start
In elderly patients with T2DM, the pro-inflammatory pathway is activated during the aging process of skeletal muscle
Biochem 271 (2004) 48724880
