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At the protein level, FOXO4-DRI apparently reduced markers tied to myofibroblasts and matrix deposition, including -SMA and Col1a1

In an inflammatory state, endothelial cells undergo activation, promoting platelet activation and adhesion [99] and localized inflammation by recruiting pro-inflammatory agents and increased leukocyte transmigration [97,98] (Fig

Because of the restrictions in use of lung tissue for histopathological analysis, only three hamsters from each group were considered for albumin analysis from the bronchoalveolar lavage fluid (BALF) and these animals' lung tissues were not included for any further analysis