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Erwin WM, Islam D, Inman RD, Fehlings MG, Tsui FW: Notochordal cells protect nucleus pulposus cells from degradation and apoptosis: implications for the mechanisms of intervertebral disc degeneration

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[ 4 ] Subsequently activated NF-B and [ 5 ] NF-B-driven expression of the inflammasome components absent in melanoma2 (AIM2), (NOD)-like leucine-rich repeat (LRR) and PYRIN domain containing3 (NLRP3), ASC-like protein, and the precursors of caspase 1, Gasdermin D, Il-1 and IL-18 allow the cell to enter the primed stage