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The pathological features of AD include -amyloid plaques, neurofibrillary tangles, and neuronal loss

| Essex, DW., et al

Transient receptor potential melastatin 2 (TRPM2) inhibition by antioxidant, N-Acetyl-l-Cysteine, reduces global cerebral ischemia-induced neuronal death

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NAC also significantly reduced the concentration of IL-1RA which is a marker of oxidative stress and increased the concentration of plasma protective cytokines IL-17A ( p = 0.012) and Vascular Endothelial Growth Factor ( p = 0.043) ( Mahakalkar et al
