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Compared to their offspring and matched controls, EL individuals exhibited a distinct metabolic profile characterized by higher levels of primary and secondary bile acidsmost notably chenodeoxycholic acid (CDCA) and lithocholic acid (LCA)lower levels of biliverdin and bilirubin, and stable levels of selected steroids

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Taken together, glutamate switches human platelets to pro-activation phenotype mediated mostly through AMPA receptors and thus targeting glutamate receptors may be a promising anti-platelet strategy.

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