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Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinsons disease

Hierarchical cluster analysis was performed using Genesis software version 1.8.1 for Windows (19)

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Notably, failure of PB1 extrusion and organelle dysfunction were discovered, with mycotoxin causing impaired PB1 expulsion at concentrations of 3050 M and toxic effects on embryos, oocytes, and cumulus cells at concentrations above 50 M (Schoevers et al., 2016