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The water solubility of HPI ranges from 13 to 17% at a neutral pH and reaches 7480% at an alkaline pH of 9 [33]

Naturally synthesised by the body from two essential amino acids L-lysine and L-methionine, it plays an important role in weight loss

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Increased heart rate

41 In a standard scenario, TMAO levels are affected by numerous factors such as diet, underlying diseases, lifestyles, and basic studies have found that TMAO may also be the causative agent of certain other cardiovascular diseases and neurological diseases, and these covariates may mask the authentic relationship between TMAO and AF as well as arrhythmia