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[15] Serious but infrequent events-such as angioedema, bronchospasm, hypotension, or urticaria-reflect IgE-mediated hypersensitivity and may require desensitization or substitution with hydroxocobalamin

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"I'm not going to speculate whether it is or it isn't, other than to say that this investigation is coming to an end." Demetriou said he hoped the joint ASADA-AFL investigation would be completed in August, ahead of the finals series in September

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