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Description
The O-GlcNAc pathway also plays a role in neurodegenerative diseases, with age-related alterations in O-GlcNAcylation levels impacting cognitive function and contributing to the progression of conditions such as Alzheimers disease (AD)

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At this point, endoarterial trophoblasts invade the spiral arteries, which permits, already from the second trimester of pregnancy, hemotrophic nutrition of the fetus [34]

Disulfiram alone functions as a radiosensitizer for pancreatic cancer both in vitro and in vivo

Brain target occupancy of LY3372689, an inhibitor of the O-GlcNAcase (OGA) enzyme, following administration of single and multiple doses to healthy volunteers
