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4-Hydroxy-2-nonenal (4-HNE) is one of the most biologically active and well-studied cell-reactive aldehydes (Dham et al., 2021)

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Several chronic, age-related conditions, including neurodegenerative diseases, mitochondrial dysfunction, diabetes, and even cancer, have been linked to inadequate levels of glutathione 3, 4
10.1080/14786419.2014.951933 56 NaczkM.ShahidiF
Cell 54 , 447454.e444 (2020)
