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There might be an obvious link to pernicious anaemia: a strong family history of PA and/or other autoimmune conditions for example

Sourcing from suppliers providing third-party Certificates of Analysis with HPLC-MS testing and endotoxin data reduces but does not eliminate this risk

10.1038/288715a0 40 PickartL.MargolinaA

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This information can inform the design of biomaterials for ACL reconstruction that mimic the natural mechanical properties of the ligament, enhancing the success of surgical interventions