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explored the role of melatonin in modulating the inflammatory response induced by LPS in mice, focusing on the expression and activity of inducible iNOS

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Grade I (mild sprain) Goals Control pain and swelling Restore knee range of motion (ROM) Begin muscle activation, particularly quads and hamstrings Gradually reintroduce load Typical plan Acute / protection phase (days 13 or until pain allows) Rest (avoid aggravating activities) Ice, compression, elevation Gentle passive / active assisted knee flexion/extension (within tolerance) Quadriceps sets (isometric contraction) Straight leg raises if pain allows Early rehab (week 12) Progress ROM (heel slides, wall slides) Light closed-chain loading (mini squats) Gentle hamstring activation Begin balance / proprioception (e.g

It helps restore natural joint function in a way that many other treatments dont