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In the TME, the ectoenzyme CD38 is a major NADase expressed on many immune cells, including myeloid cells

[DOI] [PMC free article] [PubMed] [Google Scholar] Misra S, Boylan M, Selvam A, Spallholz JE, Bjornstedt M

JAMA 331 , 3848 (2024)

The administration of polysaccharides derived from HEM has been shown to inhibit the reduction of SOD enzyme activity and improve the free radical scavenging ability of Caco-2 cells

10.21053/ceo.2024.00373 157 WangS.LiY.LiW.ZhangK.YuanZ.CaiY.et al (2021a)
