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Here the authors report a phase I clinical trial assessing the safety of clinically formulated TS in mesothelioma patients, and identify SLC7A11 as a potential mediator of TS resistance in pre-clinical models.

While use of OHB as a sole therapeutic is currently limited, with employment of a ketogenic diet a more widely used approach, recent development and testing of esterified forms of OHB have shown great promise, with the approach elevating plasma OHB while allowing consumption of normal diet
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Senescent Cell Biology and Selective Targeting Mechanisms
4-Caffeoyl-1,5-quinide in roasted coffee inhibits naloxone binding and reverses anti-nociceptive effects of morphine in mice
