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43 This suggests that this mtDNA mutation is a risk factor that requires interactions with nuclear mutations, polymorphisms or epigenetics and/or environmental triggers or modulators in order for the disease phenotype to be expressed

Inhibition of PPAR leads to serum acylcarnitine accumulation [190], whereas hepatic PPAR activation induced by energy deprivation or fibrates is associated with an increase in the carnitine concentration and a decrease in serum acylcarnitine accumulation [191, 192]

[DOI] [PubMed] [Google Scholar] 1044.Voutilainen E.K., Hantunen S., Ruusunen A., Tuomainen T.-P., Virtanen J.K

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