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Treatment also produces beneficial changes in plasma lipid profiles, decreasing total cholesterol levels by approximately 30%, bringing these values to levels comparable with normal-weight controls

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After implantation, IGF-I is produced in the human embryo (37), but until then the source of IGF-I is thought to be the female reproductive tract, and it is known that the availability of the IGF-I ligand is important for blastocyst growth in human in vitro fertilization - IVF (38)

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