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PLoS One 7, e46571

Epigenetic regulation in human cancer: The potential role of epi-drug in cancer therapy

These properties can improve drug solubility, stability, pharmacokinetics, and targeted brain accumulation while reducing systemic toxicity

Under cystine-starved conditions, GSH supplementation rescued the phosphorylation of p70S6K (T389) and S6 (S235/236) of the mTORC1 pathway and relieved the induction of phospho-GCN2 (T899), phospho-eIF2 (S51) and ATF4 of the ISR system (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 157.Radovanovic I, Braun N, Giger OT, Mertz K, Miele G, Prinz M, Navarro B, Aguzzi A
