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The disease-associated gene GDAP1 encodes for a mitochondrial outer membrane protein

18 and Supplementary Data files 16 are provided with the online version of this paper

Sayin, V

This treatment significantly reduced levodopa-induced dyskinesia scores by up to 46% in peak abnormal involuntary movements scores and 60% in total abnormal involuntary movements scores at the optimal dose (40 mg/kg), compared to free levodopa administration

Based on a four amino acid motif at the active site sequence, the encoded proteins are grouped into classical CxxC/S GRX (class I), monothiol CGFS GRX (class II), and CC-type GRX (class III), with the last sub-class being specific to land plants (Lemaire, 2004