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Iris color darkening was not observed in any patient who had a uniformly blue or brown iris color at baseline

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The administration of the antioxidant GSH diminished the activation of the IkB kinase/NF-kB pathway in an investigation utilizing peripheral blood cells from COPD patients (Figure 1) [61]

Armuzzi A, Pugliese D, Danese S, Rizzo G, Felice C, Marzo M, et al

For the activation assay, freshly isolated CD4 + CD25 + regulatory T cells were either maintained in a culture medium with 5 ng/ml -1 IL-2 or activated with 5 ng/ml -1 IL-2 and anti-mouse CD3/CD28 beads according to the manufacturers instructions (Gibco, Thermo Fisher Scientific)
