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Above all, our findings suggest that ferroptosis caused by GSH depletion-mediated lipid peroxidation contributes to SLC27A5-deficiency-induced sorafenib resistance in HCC

CrossRef Macrophage and Adipocyte Mitochondrial Dysfunction in Obesity-Induced Metabolic Diseases Liwen Wang, Jie Hu, Haiyan Zhou The World Journal of Men's Health.2021

doi: 10.1038/nrgastro.2012.225

However, during the aging process, the dysfunction and decline of VSMCs have a detrimental impact on the structural integrity of the aorta, ultimately leading to the development of transthoracic aortic aneurysms

(1998) J Mol Biol 281 : 135-147 PubMed: 9680481 Search on PubMed DOI: Primary Citation Related Structures: 1A0F PubMed Abstract: Cytosolic glutathione S-transferase is a family of multi-functional enzymes involved in the detoxification of a large variety of xenobiotic and endobiotic compounds through glutathione conjugation