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[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Mayhew DL, Mayhew JL, Ware JS

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Inhibiting HK2 curtails the first committed step of glycolysis, reducing glucose-6-phosphate accumulation and its diversion into the PPP, while LDHA blockade prevents pyruvate-to-lactate conversion, averting extracellular acidosis and mitochondrial fragmentation
