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Tautenhahn R, Cho K, Uritboonthai W, et al

172 However, a Phase III randomized controlled study (NCT01767155) found that AEZS-108 did not improve OS and PFS compared with doxorubicin or dostarlimab as second-line therapy for locally advanced, recurrent, or metastatic EC

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Consequently, higher concentrations of sulforaphane are necessary to induce cell cycle arrest and apoptosis, which are desirable outcomes in a chemotherapeutic context of inhibition

doi: 10.1046/j.1365-2672.1999.00844.x
