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FIGURE 1 Characterization of differentiated hepatocyte-like cells Human iPSCs were first differentiated into definitive endoderm (DE) cells, followed by hepatoblast specification and subsequent maturation into HLCs

Recently, a hypothesis has been proposed that may also implicate pathogens in the development of Downs syndrome (DS) and related Downs syndrome Alzheimers disease (DSAD) (Norins, 2022)

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2 = 1620 intralobular or perivascular leukocytes/HPF