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In patients with wounds, nociceptive and neuropathic pain frequently coexist [35]

SS-31 (elamipretide) , a mitochondria-targeted peptide that stabilizes cardiolipin to support energy production, became the first FDA-approved mitochondrial therapeutic in 2025, though only for the rare Barth syndrome, with the brain rationale still mechanistic and no cognitive trials

How It Works Epithalon (Epithalamin analog) is a pineal tetrapeptide that has been shown in preclinical and early human work to activate telomerase, extend telomere length, modulate aging biomarkers, and restore melatonin secretion and pineal cell function

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The control group demonstrated minimal improvement and recovery