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In one study involving 6,455 treatment courses of acetylcysteine, it doesnt seem that there was any serious harm from anaphylactoid reactions (e.g., death)

(1992) Tyrosine-7 is an essential residue for the catalytic activity of human class pi glutathione 5-transferase: chemical modification and site-directed mutagenesis studies, Biochem

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In addition to this, LSPC also does not require any complicated setup (e.g., vacuum chambers) and processing procedures since it only generally needs a target (carbon, in this case), the solvent of choice, and the laser to operate