The Carnitine Shuttle
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Description
This response likely limits iron-mediated oxidative damage when Fe-S cluster assembly is impaired
Apart from reducing ROS, TIGAR also may limit autophagy activation through the mTOR-S6KP70 signaling pathway (Zhang et al., 2019)
[DOI] [PubMed] [Google Scholar] (68).Ma D, Cook DN, Alberti M, Pon NG, Nikaido H, and Hearst JE (1995) Genes acrA and acrB encode a stress-induced efflux system of Escherichia coli
Taken on their own and in moderation, theyre generally safe for most people
F.BartelD
