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A high-resolution haplotype structure for the GSR gene and the association of the individual SNPs and haplotypes with the GSR gene in Han Chinese (CHB) individuals from the International Hapmap Project has been defined

[DOI] [PMC free article] [PubMed] [Google Scholar] 40.De Koning E.J., Van der Zwaluw N.L., Van Wijngaarden J.P., Sohl E., Brouwer-Brolsma E.M., Van Marwijk H.W.J., Enneman A.W., Swart K.M.A., Van Dijk S.C., Ham A.C., et al
Seven patients with idiopathic dilated cardiomyopathy and moderate to severe heart failure were studied at baseline, after three months of therapy with human growth hormone, and three months after the discontinuation of growth hormone
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To validate the functional importance of the secondary IGF1-binding site, we introduced Y487A and R488A mutations into IGF1R, and tested their effects on IGF1R activation