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Therefore, the most important function of GPX1-4 is to prevent oxidative stress by catalyzing the reduction of H 2 O 2 or organic hydroperoxides

However, pretreatment with GSSSG for 1 h inhibited the LPS-induced enhancement of TAK1 phosphorylation at the time points examined (Fig

Western blot analysis Cells were washed twice with cold PBS and lysed in RIPA buffer (R0278, Sigma-Aldrich), followed by vortexing and incubation on ice for 30 min

Consequently, this highly redundant organization might contribute to the clinical presentation of PD

Until present, excessive VLCFA has been considered the causative factor of oxidative stress and inflammation in X-ALD (73)