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Taken together, the mutational status of p53 is an important factor in determining the response of GBM to p62-mediated targeted ferritin therapy (Zhu et al., 2021)

The benefit obtained seems dose dependent and mean benefits of 7.0 to 8.0 cm have been reported with higher doses of 0.32 to 0.4 mg/kg/week [2,3,9]

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