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Additionally, GHK's influence on the miR-339-5p/VEGFA axis played a crucial role in preventing neuronal apoptosis following ICH injury

[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Kim B., Seong K.Y., You I., Selvaraj V., Yim S.G., OCearbhaill E.D., Jeong U., Yang S.Y

The K m values of the Y398A variant toward tyrosine and DOPA are 5- and 2-fold higher than that of the WT enzyme, respectively

This epigenetic regulation involves copper-dependent activation of cellular pathways including enhanced DNA repair, increased antioxidant enzyme production, and stimulation of regenerative processes while simultaneously suppressing inflammatory and destructive gene programs
