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The primary antibodies employed were: P53 (Proteintech, 60283-2-Ig), pSer46-P53 (CST, 2521), FOXO4 (Proteintech, 21535-1-AP), P21 (CST, 2947), P16 (CST, 18769), BAX (CST, 2772), BCL2 (CST, 3498), Ki-67 (Proteintech, 84192-4-RR), Lamin B (CST, 13435), Cleaved Caspase 3 (CST, 9664), -H2AX (Abcam, ab81299), and GAPDH (Abcam, ab8245) as an internal reference for normalizing protein expression levels

SOD2 expression lentivirus (SOD2) significantly increased, while SOD2 knockdown lentivirus (shSOD2) significantly decreased, SOD2 mRNA levels (see Figure 1C)

7 In more resistant cases, elevations in markers such as IL-6, TNF-alpha, granulocytes, and increased microglial activity have been reported

In research settings, dosages are typically calculated based on the subject's body weight and are measured in micrograms (mcg)

Compared to ingredients that bank on trends, GHK-Cu has decades of research that support its role in skin repair, regeneration, and collagen production