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Some cancers, particularly those affecting the stomach or intestines, may interfere with B12 absorption

Studies have revealed that mice lacking ZIP14 display a disruption in the tight junction complex and increased permeability, potentially due to impaired zinc-dependent activation of ZnR/GPR39

In: Hunter C, Johnson K, Muss H, editors

They reported that this complex effectively circumvents drug resistance by raising the concentration of the reactive oxygen species and permeability of the lysosomal membrane in tumour cells [263]

There were mostly L-NAMEs and L-arginines opposite effects and, less frequently, L-NAMEs and L-arginines parallel effects [11,29] (Table 2)