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Gene-level P values are from the Seurat Wilcoxon rank-sum test, and pathway P values are from limma

GUSTAVO BOUNOUS Immunotec Hosts a Scientific Symposium at McGill University and Launchesther Dr

doi: 10.1155/2022/3408660 59

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Several urinary metabolites derived from cytochrome P450 2E1 mediated bioactivation of furan to the highly reactive intermediate cis -2-butene-1,4-dial (BDA) and subsequent reaction of BDA with cellular nucleophiles such as free or protein-bound lysine and cysteine residues and glutathione (GSH) have been suggested as potential biomarkers of furan exposure (Kellert et al