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Future research should differentiate between symptomatic and asymptomatic infected individuals, select specific probiotics or their fermented products, utilize widely studied strains, standardize experimental protocols (including dosage, duration, and clinical endpoints), and assess the long-term effects of probiotic interventions

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An excess of ROS may cause the oxidation of macromolecules and organelles in the body, leading to oxidative stress

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The above individual findings demonstrate a significant immunological neuroendocrine disruption with the presence of chronic inflammation, neurotrophic depletion, and emotional disturbance as seen in AECOPD [96]

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As we recently reported, an easy method to measure GSH within cells is to detect the conjugate GS-NEM by UV/vis-HPLC [34]

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