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doi: 10.1371/journal.pone.0009217
This was first demonstrated by an in vitro study in which the treatment of HUVECs with a Cu chelator, tetraethylenepentamine (TEPA), suppressed the expression of a group of HIF-1 target genes such as BNIP3 and VEGF, but did not affect other HIF-1 target genes such as IGF-2 [132]
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The cystine/glutamate antiporter system xc in health and disease: from molecular mechanisms to novel therapeutic opportunities
Intranasal medication delivery for children: a brief review and update
