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Dihexa amplifies HGF/c-Met signaling to promote the physical construction of new synaptic connections (spinogenesis)

This enhanced efficacy in obesity suggests the compound may normalize dysfunctional hypothalamic signaling present in obese states

plantarum TIFN101 modulated gene transcription pathways related to tight- and adhesion junction protein synthesis and degradation, including actinin alpha-4, metalloproteinase-2 ( et.al

krlec, K., Ruman, R., Jarc, E., Sikiri, P., vajger, U., Petan, T., Perii Nanut, M., trukelj, B., & Berlec, A

[DOI] [PubMed] [Google Scholar] 78.Petek M., Sikiric P., Anic T., Buljat G., Separovic J., Stancic-Rokotov D., Seiwerth S., Grabarevic Z., Rucman R., Mikus D., et al
