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From a translational perspective, integrative biomarker panels combining genetic, epigenetic, and exposure data could enable early risk prediction and patient stratification

Emerging translational strategies These include SGLT2 inhibitors, PARP inhibitors, necroptosis blockers [216], ferroptosis inhibitors [153], and NLRP3-targeting compounds [59, 60, 145], which have demonstrated significant efficacy in experimental models and, in selected settings, preliminary benefits in clinical studies [153, 216]

Ergothioneine Protects against Neuronal Injury Induced by -amyloid in Mice

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[DOI] [PubMed] [Google Scholar] 103.Mahfoud R., Maresca M., Garmy N., Fantini J